Mebendazole is a broad-spectrum anthelmintic medication, meaning it is effective against various types of parasitic worms. It belongs to the benzimidazole class of drugs and is primarily used to treat intestinal worm infections. These commonly include pinworm (threadworm), roundworm, hookworm, and whipworm. In some cases, it may also be used off-label for other less common worm infestations.
The primary mechanism of action of<!--td {border: 1px solid #cccccc;}br {mso-data-placement:same-cell;}-->Mebendazole for Humans involves disrupting the worms' ability to absorb glucose, which is their essential source of energy. By inhibiting glucose uptake, the drug depletes the worms' energy reserves, leading to their immobilization and eventual death. Mebendazole also interferes with the formation of microtubules in the worms' intestinal cells, further hindering their function and reproduction.
Mebendazole is typically administered orally, often as a chewable tablet that can also be swallowed whole or crushed and mixed with food.The dosage and duration of treatment depend on the specific type of worm infection being treated. For instance, pinworm infections often require a single dose, while other infections may necessitate treatment for several consecutive days. It is crucial to adhere strictly to the prescribed dosage and complete the full course of treatment to ensure the complete eradication of the parasitic infection and to prevent potential recurrence.
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